16 Fast Food Chains With The Highest-Protein Pizza

Whether you're trying to incorporate protein maxxing into your food routine or just want a more filling slice on pizza night, there are abundant high-protein options when you're looking for a fast-food pie. Regardless of whether you're splurging at a more premium takeout spot or hitting up a budget pizza chain, you can readily get the power-up you're looking for, nicely packaged into that delicious specialty that is one of America's most popular foods.

While this list hones in on specific pizzas offered by U.S. fast food chains, it's actually easy to turn up the protein factor on any takeout pie, including piling on extra cheese and meat (contrary to the popular saying, too much of a good thing can only be great when it comes to pizza!). Some creative additions can significantly power up your pie, too, including thinking outside the mozzarella box in terms of cheese. Parmesan and Romano are excellent options when you want more protein, as both are very high in that macronutrient, and many pizza spots have them on hand. Less typical add-ons like nuts, egg, seafood like crab meat and shrimp, and even beans (reminiscent of the viral pizza beans craze) can also turn up the protein content if your favorite takeout place has them. While vegetables aren't typically top of mind concerning protein, various veggies contribute respectable amounts, including peas, broccoli, artichoke hearts, and spinach. So, if your preferred pizza isn't particularly high in protein, now you know some ways to turn it up a few notches.

Come along on this fast-food journey as we deliver the goods on where the highest-protein pizza options are to be found. Did your favorite takeout spot make the list?

It seems appropriate to begin with America's very first pizza chain, a joint called Shakey's Pizza Parlor, which had hundreds of locations at its heyday and now has 43 remaining restaurants, as of September 2026. At any one of them, you can grab a large Ultimate Meat pizza on pan crust, which serves up a hefty 18 grams of protein per serving and comes topped with Italian sausage, ground beef, pepperoni, ham, salami, and bacon.

A mammoth amount of protein is ready to be devoured at Rosati's Pizza, where a Meat Classic Stuffed Pizza packs just under 61 grams per slice and 486 grams in the full pie. This behemoth pizza features pepperoni, sausage, Canadian bacon, and ground beef stuffed between double crusts and then baked and topped off with sauce.

A different approach to power-packed pizza can be found at the multistate chain Giordano's, where a 6-inch, personal-sized Stuffed Deep Dish Pizza With Sausage packs a whopping 53 grams of protein, while a pepperoni-topped version has 49 grams and a plain cheese has 51. Designed to serve one person, these Giordano's creations feature an additional crust layer between the toppings and the pizza sauce, resulting in a pie that's much thicker and taller (and more filling) than the norm. Bonus: A frozen version of these mighty pies can be shipped directly to you if you don't have a Giordano's nearby.

Pizza just doesn't get much faster than when you can grab a slice or a full pie while pumping your gas, and Hunt Brothers Pizza serves up piping hot options through thousands of convenience store locations across 33 U.S. states. Among the offerings, you can grab a Hunk A Pizza-sized serving of Double Cheese Pizza (which is a quarter of an entire pie) with a whopping 30 grams of protein — brought to you, in part, by the two whole cups of extra cheese that come piled on top.

Among the pizzas Sbarro dishes up across 28 countries (including the nation where it was founded, the U.S.), the chain's Mama's Meatball pie packs approximately 29 grams of protein into one slice of the XL NY size. This meaty option includes hearty meatballs, whole milk mozzarella, dollops of ricotta cheese, and San Marzano-style tomato sauce dotted with tomato chunks.

Another protein-rich convenience store pie comes from Casey's, which is both a convenience store chain and the fifth-largest fast-food pizza brand in the United States, combining both concepts under one roof. Among its offerings, the pizzeria portion of the business has a dynamite Bacon Breakfast Pizza that delivers 29 grams of protein in the Warmer Slice size, topped with your choice of cheese sauce or sausage gravy, scrambled eggs, bacon, and both mozzarella and cheddar cheeses — and, for even more protein power, you can add breakfast sausage and ham for an upcharge.

The slices at Jet's Pizza are big, with some segments representing one-quarter of the pie, and those hefty wedges bring big protein. A large NY-style slice of Aloha BBQ Chicken pizza serves up a whopping 28 grams of protein and features barbecue sauce, grilled chicken, pineapple, bacon, and mozzarella cheese (pineapple may be a controversial pizza ingredient, but with protein power like this, why waste time debating when you could be scarfing?).

Godfather's Pizza, that mobster-themed pizzeria that has been serving up tasty pies for more than 50 years, has a protein-packed offer you can't refuse. The chain's jumbo Chicken Taco Pie, heaped with taco sauce, chicken, lettuce, tomatoes, cheddar and mozzarella cheeses, plus extra cheddar, delivers a heaping 25 grams of protein per slice — even Peter Clemenza (aka "Fat Pete," aka "Fat Clemenza") of "The Godfather" film franchise might be impressed. Don't like taco pizza? No problem — the Super Combo and Wild Wild West BBQ have the same protein.

Mashing up two fast-food favorites, pizza and burgers, Hungry Howie's is serving up a Bacon Cheddar Cheeseburger Pizza that has ground beef, bacon, cheddar, mozzarella — and 18 grams of protein per slice when you order a large pie. The protein pack goes up even more when you opt for an extra-large pizza, increasing to approximately 25 grams per wedge. Want something more traditional? The Three Cheeser Pepperoni Pleaser has the same protein per slice.

Next up is the leading pizza chain in the U.S. in terms of units and sales, as of 2026 (per PMQ Pizza): Domino's. At this global pizza giant, the Spicy Chicken Bacon Ranch is a protein-loaded pie featuring grilled chicken breast, creamy ranch sauce, smoked bacon, jalapeño peppers, provolone cheese, mozzarella, and a buffalo sauce drizzle, and when you opt for the extra-large size, you reap the benefits of 21 grams of protein per slice. For something with tons of meat and veggies, try the ExtravaganZZa, which boasts the same protein.

A spicy mashup of two Italian favorites is offered up at Toppers Pizza, where a large slice of Buffalo Chicken Mac 'N Cheese pizza on hand-tossed crust delivers 21 grams of protein. This uber-cheesy marriage of pizza and pasta features creamy cheese sauce topped with macaroni noodles, a blend of Wisconsin mozzarella and cheddar cheeses, buffalo chicken, applewood smoked bacon, and a buffalo sauce drizzle.

Nationwide chain Marco's Pizza brings on the protein power with its All Meat Pizza, with a large pie dishing out 35 grams of protein per slice. The meaty mouthful comes topped with pepperoni, ham, Italian sausage, and bacon to make pizza time a tasty and filling occasion.

At the home of "Pizza! Pizza!" you can get a whopping 159 grams of protein in a full-sized Detroit-Style Deep Dish 3 Meat Treat, which breaks down to just around 20 grams of protein per piece when divided by the eight included slices. Veering from the Little Caesars pizza norm with square-shaped pieces rather than triangular, the 3 Meat Treat comes topped with pepperoni, Italian sausage, and bacon, with the toppings stretching right to a scrumptious edge that is caramelized with cheese.

Over at Pizza Hut, a classic menu item first introduced in the late 1980s is still serving up big protein in the form of lots and lots of meat. The Meat Lovers pizza comes loaded with pepperoni, Italian sausage, slow-roasted ham, applewood smoked bacon, pork, and beef, and if you get a large size with stuffed crust — another concept Pizza Hut brought to mainstream diners — you'll gobble up a hearty 19 grams of protein thanks to that ring of cheese on the outer edge.

Papa John's is powering up customers with offerings like its Philly Cheesesteak Pizza, which delivers 19 grams of protein per slice when you opt for the Epic Stuffed Crust as your foundation. The Philly includes Philly steak, onions, green peppers, ranch sauce, and a three-cheese blend to enjoy, devour, and fuel up with. And the Pepperoni, Sausage, and Six Cheese in the Epic Stuffed Crust? That gets 20 grams.

You don't need to be a knight or a lady-in-waiting to enjoy a piping hot slice at medieval-themed restaurant chain Round Table Pizza. Royalty, gentry, and peasants alike can get a protein power-up with a wedge of Montague's All Meat Marvel pizza on Pan Crust, which features a meaty topping feast of Italian sausage, pepperoni, salami, and linguiça sausage and serves up 18 grams of protein per slice.